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    Steric hindrance at a given atom in a molecule is the congestion caused by the physical presence of the surrounding ligands, which may slow down or prevent reactions at the atom.

    eg. 1:

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    In 1, the carbonyl carbon is bonded to two hydrogen atoms. In 2, it is bonded to a hydrogen atom and a methyl group. Since the methyl group is larger than the hydrogen atom, steric hindrance is greater at the carbonyl carbon in High High Alethea Alethea Alethea High Alethea High 2MJ AH8111 ZOOM RUNNING TENACITY 001 SHOE ZfpqO1Zx than that in 1.

    eg. 2:

    In 1, the nitrogen atom is bonded to three hydrogen atoms; in High Alethea High Alethea High Alethea Alethea High 2, it is bonded to three methyl groups. A methyl group is larger than a hydrogen atom. Thus, the steric hindrance at the nitrogen atom in 2Runni Walking Men Sport Shoes Summer Sneakers Footwear Spring Lace Male Brand Up XPS4qq is greater than that in 1.

    eg. 3:

    In 3, C1 is doubly bonded to a carbon atom and singly bonded to two hydrogen atoms, whereas C2 is doubly bonded to a carbon atom and singly bonded to two ethyl groups. An ethyl group is larger than a hydrogen atom. Thus, the steric hindrance at C2 is greater than that at C1.

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