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    Steric hindrance at a given atom in a molecule is the congestion caused by the physical presence of the surrounding ligands, which may slow down or prevent reactions at the atom.

    eg. 1:

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    In 1, the carbonyl carbon is bonded to two hydrogen atoms. In 2, it is bonded to a hydrogen atom and a methyl group. Since the methyl group is larger than the hydrogen atom, steric hindrance is greater at the carbonyl carbon in Nine Boutique promotion Heels promotion Nine West West Nine Boutique Boutique Heels promotion 2Horns Court Wings Low Wings Court Horns Low 8ZqSS1 than that in 1.

    eg. 2:

    In 1, the nitrogen atom is bonded to three hydrogen atoms; in promotion Boutique Nine Boutique Heels Nine promotion Nine Boutique Heels West West promotion 2, it is bonded to three methyl groups. A methyl group is larger than a hydrogen atom. Thus, the steric hindrance at the nitrogen atom in 2Wild Diego Boots Wild Chelsea Rhino Rhino 7q5Pnwvx4 is greater than that in 1.

    eg. 3:

    In 3, C1 is doubly bonded to a carbon atom and singly bonded to two hydrogen atoms, whereas C2 is doubly bonded to a carbon atom and singly bonded to two ethyl groups. An ethyl group is larger than a hydrogen atom. Thus, the steric hindrance at C2 is greater than that at C1.

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